MRI research at the University of Winnipeg

The MRI Group focuses on using Magnetic Resonance Imaging (MRI) to diagnose, understand, and evaluate treatments of central nervous system disorders. We do this through a better understanding of how MRI metrics correlate with anatomy and function.

The research in this lab is performed in 2 centres

1. In Vivo Experimental Animal Magnetic Resonance Micrscopy Centre located at the Health Sciences Centre.
Pictured at right is the Martin MRI Group near a 7 T Horizontal Bore Bruker MR scanner which is located at HSC.

2. The University of Winnipeg MRI Laboratory
Pictured at right is the Martin MRI Group in the MRI Laboratory located at the University of Winnipeg.

Recent publications from the lab

Herrera SL, Mercredi ME, Buist R, Martin M Inferring diameters of spheres and cylinders using interstitial water, Magn Reson Mater Phy (2018) 31(5):609-620.

Mercredi ME, Martin M Toward faster inferences of micron-scale axon diameters using Monte Carlo simulations, Magn Reson Mater Phy (2018) 31(4):511-530.

Whittaker HT, Zhu S, Di Curzio DL, Buist R, Li XM, Noy S, Wiseman FK, Thiessen JD Martin M T_1, diffusion tensor, and quantitative magnetization transfer imaging of the hippocampus in an Alzheimer's disease model, Magnetic Resonance Imaging (2018) 50: 26-37.

Mercredi ME, Vincent TJ, Bidinosti CP, Martin M Assessing the accuracy of using oscillating gradient spin echo sequences with AxCaliber to infer micron-sized axon diameters, Magn Reson Mater Phy (2017) 30:1-14.

Vincent DE, Wang T, Magyar TAK, Jacob PI, Buist R, Martin M Birdcage volume coils and magnetic resonance imaging: a simple experiment for students. Journal of Biological Engineering (2017) 11:41.

Snow W, Dale R, O'Brien Moran Z, Buist R, Peirson D, Martin M, Albensi BC, In Vivo Detection of Grey Matter Neuropathy in the 3xTg mouse model of Alzheimer's disease with Diffusion Tensor Imaging, Journal of Alzheimer's Disease (2017) 58(3):841-853.

Matsuda K, Lopes-Calcas A, Honke M, O'Brien Moran Z, Buist R, West M, Martin M, Ex vivo tissue imaging for Radiology-Pathology correlation: A pilot study with a small bore 7 T MRI in a rare pigmented ganglioglioma exhibiting complex MR signal characteristics associated with melanin and hemosiderin. Journal of Medical Imaging (2017) 4(3): 0360001

Beltrano W, O'Brien-Moran Z, Herrera SL, Martin M Comparison of tractography in mouse models of multiple sclerosis and Alzheimer's disease, STEM Fellowship Journal (2017) 3(1): 37-46.

Herrera SL, Palmer VL, Whittaker H, Cargian Smith B, Kim A, Shcellenberg AE, Thiessen JD, Buist R, Del Bigio MR, Martin M Damage to the Optic Chiasm in Myelin Oligodendrocyte Glycoprotein - Experimental Autoimmune Encephalomyeletis Micei, Magnetic Resonance Insights 2014:7 23-31.

Hayes K, Buist R, Vincent TJ, Thiessen JD, Zhang Y, Zhang H, Wang J, Summers AR, Kong J, Li XM, Martin M, Comparison of Manual and Semiautomated Segmentation Methods to Evaluate Hippocampus Volume in APP and PS1 Transgenic Mice obtained via in-vivo Magnetic Resonance Imaging, Journal of Neuroscience Methods, 221, 2014.